TY - JOUR
T1 - Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition
AU - Latin American Trans-Ancestry INitiative for OCD genomics (LATINO)
AU - Brazilian Obsessive-Compulsive Spectrum Work Group (GTTOC)
AU - Pinciotti, Caitlin M.
AU - Avery, Juliana
AU - Zhang, Chencheng
AU - Berrones, Dayan
AU - Cruz, Vanessa Zavala
AU - Wiese, Andrew D.
AU - Anderberg, Jacey L.
AU - Frederick, Renee M.
AU - Miño, Tomás
AU - Lanzagorta, Nuria
AU - Restrepo, Juan Camilo
AU - Ochoa-Panaifo, Marcos E.
AU - Adorno, Victor R.
AU - Agostini, Victoria
AU - Aguilar, William W.
AU - Aguirre, Cinthia
AU - Alvarado-Quiroz, Valentina
AU - Ancalade, Na Eshia
AU - Anciburo L, Maria E.
AU - Aponte, Diego
AU - Arellano Espinosa, Alejandro A.
AU - Arnold, Paul D.
AU - Carmelo, Brygith Asenjo
AU - Atkinson, Elizabeth G.
AU - Avanesyan, Tatevik
AU - Ayala, Jose N.
AU - Aziz, Hala
AU - Barbieri Aguirre, Tania L.
AU - Barrera, Cynthia N.
AU - Barrero Contreras, Julian A.
AU - Barry, Kelly
AU - Belanger, Amanda N.
AU - Benitez, Laura M.
AU - Best, John R.
AU - Bigdeli, Tim B.
AU - Bommiasamy, Hemamalini
AU - Borda, Tania
AU - Boyajian, Laura
AU - Muñoz, Diego Briceño
AU - Browning, Lauren
AU - Burton, Christie L.
AU - Busto, Carolina
AU - Buxbaum, Joseph D.
AU - Calderón Rivera, Ricardo E.
AU - Callahan, Jennifer L.
AU - Camacho Gomez, Carlos A.
AU - Obando, Diana
AU - Quiroz-Padilla, Maria F.
AU - Trujillo, Angela
AU - Storch, Eric A.
A2 - Muñoz, Josselyn S.
N1 - Publisher Copyright:
© 2025 Elsevier B.V.
PY - 2025/12/1
Y1 - 2025/12/1
N2 - The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is considered the primary instrument for assessing the presence and severity of obsessive-compulsive disorder (OCD). Conceptual and empirical critiques inspired the development of an updated version of the instrument, the Yale-Brown Obsessive Compulsive Scale-Second Edition (Y-BOCS-II), with a higher ceiling of OCD severity to better differentiate between severe and the most debilitating OCD presentations, among other revisions. The Y-BOCS-II has demonstrated sound psychometric properties across diverse samples. Empirically derived severity benchmarks have been proposed for the original Y-BOCS, yielding somewhat different ranges than what has been commonly used in clinical and research settings, yet severity benchmarks for the Y-BOCS-II have yet to be established. Using a diverse, pooled sample of 2982 children and adults with OCD or obsessive-compulsive and related concerns across 13 countries, receiver-operating characteristic (ROC) analyses yielded severity benchmarks that largely mirrored the original Y-BOCS at the lower range of scores and extended the previously established benchmarks at the higher range of scores, owing to the increased ceiling of the instrument. The optimal benchmark ranges were determined as: non−/sub-clinical (0–14), mild (15–21), moderate (22–34), severe (35–50). Similar benchmarks were present across sex and age groups, and their accuracy was adequate in both a holdout sample and an independent sample of OCD patients from China (n = 78). Limitations and implications for the use of the Y-BOCS-II in clinical and research settings are discussed.
AB - The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is considered the primary instrument for assessing the presence and severity of obsessive-compulsive disorder (OCD). Conceptual and empirical critiques inspired the development of an updated version of the instrument, the Yale-Brown Obsessive Compulsive Scale-Second Edition (Y-BOCS-II), with a higher ceiling of OCD severity to better differentiate between severe and the most debilitating OCD presentations, among other revisions. The Y-BOCS-II has demonstrated sound psychometric properties across diverse samples. Empirically derived severity benchmarks have been proposed for the original Y-BOCS, yielding somewhat different ranges than what has been commonly used in clinical and research settings, yet severity benchmarks for the Y-BOCS-II have yet to be established. Using a diverse, pooled sample of 2982 children and adults with OCD or obsessive-compulsive and related concerns across 13 countries, receiver-operating characteristic (ROC) analyses yielded severity benchmarks that largely mirrored the original Y-BOCS at the lower range of scores and extended the previously established benchmarks at the higher range of scores, owing to the increased ceiling of the instrument. The optimal benchmark ranges were determined as: non−/sub-clinical (0–14), mild (15–21), moderate (22–34), severe (35–50). Similar benchmarks were present across sex and age groups, and their accuracy was adequate in both a holdout sample and an independent sample of OCD patients from China (n = 78). Limitations and implications for the use of the Y-BOCS-II in clinical and research settings are discussed.
UR - https://www.scopus.com/pages/publications/105010693423
U2 - 10.1016/j.jad.2025.119719
DO - 10.1016/j.jad.2025.119719
M3 - Artículo
C2 - 40541829
AN - SCOPUS:105010693423
SN - 0165-0327
VL - 390
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
M1 - 119719
ER -